Enalapril Maleate

  • Commonly Prescribed For: Heart and/or Kidney Conditions
  • Species: Dogs and Cats
  • Therapeutic Class: Vasodilator

General Drug Information and Indications:

  • Enalapril Maleate is a vasodilator used primarily in dogs and cats to manage heart and kidney
  • conditions by causing vasodilation of the blood vessels. This action helps to reduce the workload
  • on the heart and lower blood pressure. It is often prescribed in conjunction with other
  • medications like diuretics or beta blockers to enhance efficacy. While FDA-approved for use in
  • dogs, enalapril is also commonly used off-label in cats to treat hypertension and heart conditions.

Administration:

  • Administer enalapril exactly as prescribed by your veterinarian. If a dose is missed, give it as
  • soon as possible unless it's near the time for the next dose; do not double the dose. Always wash
  • your hands after handling this medication.
  • Side Effects:
  • Discuss any side effects with your veterinarian immediately. Common side effects include low
  • blood pressure, dizziness, weakness, and stomach upset. Less frequently, kidney damage or
  • alterations in blood potassium levels may occur.
  • Precautions:
  • Enalapril should be kept out of reach of children and only given to the pet for which it was
  • prescribed. Regular monitoring of blood chemistry, kidney function, and blood pressure is
  • necessary due to the potential worsening of underlying kidney issues and other health risks. Special
  • care is needed in pets with decreased liver or kidney function, as well as diabetic animals, as
  • enalapril may alter insulin requirements.
  • Drug Interactions:
  • Careful monitoring is essential when enalapril is used in conjunction with other medications,
  • especially diuretics, and other vasodilators, due to risks of significant blood pressure drops and
  • changes in potassium levels. NSAIDs, including aspirin, should be avoided as they increase the
  • risk of kidney damage.
  • Overdose:
  • In the event of an accidental overdose, contact your veterinarian or the A.S.P.C. A's Animal
  • Poison Control Center at 888.426.4435. If a human ingests enalapril by mistake, contact the
  • National Capital Poison Center at 800.222.1222. Always bring the prescription container when
  • seeking treatment.
  • Storage:
  • Storage requirements for enalapril maleate may vary by the strength and dosage form. Consult
  • the medication label or your pharmacist for proper storage instructions.